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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > DSG3 Antibody

DSG3 Antibody

LM20277
货号 货期 规格 / 价格 询价

DSG3 Antibody

品牌

Leading Biology

货号

LM20277

产品分类

单克隆抗体

研究领域

产品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

形式

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. ; ;

纯度

Mouse

复溶

1. J Dermatol Sci. 2012 Feb;65(2):102-9. 2. Am J Pathol. 2009 May;174(5):1629-37.

储存条件

Human

储存溶液

Desmoglein-3, 130 kDa pemphigus vulgaris antigen, PVA, Cadherin family member 6, DSG3, CDHF6

应用

E~~1/10000 WB~~1/500 - 1/2000 FC~~1/200 - 1/400 IHC~~1/200 - 1/1000

产品描述

Function Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Cellular_Location Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome Tissue_Location Epidermis, tongue, tonsil, esophagus and carcinomas

数量

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