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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > DOCK4 Antibody (monoclonal) (M03)

DOCK4 Antibody (monoclonal) (M03)

LM20275
货号 货期 规格 / 价格 询价

DOCK4 Antibody (monoclonal) (M03)

品牌

Leading Biology

货号

LM20275

产品分类

单克隆抗体

研究领域

产品概述

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

形式

This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized.

浓度

DOCK4 (NP_055520, 1867 a.a. ~ 1966 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

纯度

mouse

试剂准备

Clear, colorless solution in phosphate buffered saline, pH 7.2.

复溶

Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614. Characterization of a family with rare deletions in CNTNAP5 and DOCK4 suggests novel risk loci for autism and dyslexia. Pagnamenta AT, et al. Biol Psychiatry, 2010 Aug 15. PMID 20346443. Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening. Voss M, et al. BMC Immunol, 2009 Oct 6. PMID 19807924. Cell migration is regulated by platelet-derived growth factor receptor endocytosis. Kawada K, et al. Mol Cell Biol, 2009 Aug. PMID 19528233. High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility. Maestrini E, et al. Mol Psychiatry, 2010 Sep. PMID 19401682.

储存条件

Human

储存溶液

Dedicator of cytokinesis protein 4, DOCK4, KIAA0716

应用

WB~~1:500~1000

数量

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