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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > DCTN4 Antibody

DCTN4 Antibody

LM20253
货号 货期 规格 / 价格 询价

DCTN4 Antibody

品牌

Leading Biology

货号

LM20253

产品分类

单克隆抗体

研究领域

产品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

纯度

Mouse

复溶

Cell. 2008 Dec 26;135(7):1189-200. J Biol Chem. 2006 May 19;281(20):14006-14.

储存条件

Human, Mouse

储存溶液

Dynactin subunit 4, Dyn4, Dynactin subunit p62, DCTN4

应用

E~~1/10000 WB~~1/500 - 1/2000 IF~~1/200 - 1/1000 FC~~1/200 - 1/400 IHC~~1/200 - 1/1000

产品描述

Function Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton. Cellular_Location Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=In skeletal muscles, demonstrates a punctate distribution along costameres (By similarity). Has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin. Overexpression does not disrupt microtubule organization or the integrity of the Golgi but does cause both cytosolic and nuclear distribution, suggesting that this polypeptide may be targeted to the nucleus at very high expression levels.

数量

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