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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > Cytokeratin-10 Antibody

Cytokeratin-10 Antibody

LM20233
货号 货期 规格 / 价格 询价

Cytokeratin-10 Antibody

品牌

Leading Biology

货号

LM20233

产品分类

单克隆抗体

研究领域

产品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

形式

Cytokeratin 10 (CK10) is a heterotetramer of two type I and two type II keratins. CK10 is typically associated with cytokeratin 1 (CK1). CK10 is expressed in all suprabasal cell layers, and it is part of the acidic/high molecular weight keratin subfamily. Defects in CK10 cause Epidermolytic hyperkeratosis (EHK), a hereditary skin hereditary skin disorder characterized by blistering and a marked thickening of the stratum corneum (1). CK10 has also been linked to cause annular epidermolytic ichthyosis (AEI), also known as cyclic ichthyosis with epidermolytic hyperkeratosis. CK10, along with CK14, 15, 16, and 20, can be used to determine if a neoplasm originated from an epithelial or non-epithelial origin, such as the determination of metastatic malignant tumors of epithelial origin (2).

浓度

A synthetic peptide corresponding to residues in the C-term of human Cytokeratin 10 was used as immunogen.

纯度

Rabbit

试剂准备

50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

复溶

1. McGowan, K, et al; Journal of Investigative Dermatology 126:1013<br>2. Lin, Y, et al; Modern Pathology 17:1129<br>

储存条件

Human

储存溶液

Keratin, type I cytoskeletal 10, Cytokeratin-10, CK-10, Keratin-10, K10, KRT10, KPP

应用

WB~~1:500

产品描述

Tissue_Location Seen in all suprabasal cell layers including stratum corneum

数量

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