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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > CCRK Antibody (N-term)(Ascites)

CCRK Antibody (N-term)(Ascites)

LM20126
货号 货期 规格 / 价格 询价

CCRK Antibody (N-term)(Ascites)

品牌

Leading Biology

货号

LM20126

产品分类

单克隆抗体

研究领域

产品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

形式

Required for high-level Shh responses in the developing neural tube. Together with BROMI, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity). Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'.

浓度

Purified His-tagged CCRK protein was used to produced this monoclonal antibody.

纯度

Mouse

试剂准备

Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

复溶

Liu Y., et al. J. Biol. Chem. 279:4507-4514(2004). Wang L.Y., et al. Oncogene 31:2907-2918(2012). Qiu H., et al. Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases. Ota T., et al. Nat. Genet. 36:40-45(2004). Humphray S.J., et al. Nature 429:369-374(2004).

储存条件

Human

储存溶液

Cyclin-dependent kinase 20, CDK-activating kinase p42, CAK-kinase p42, Cell cycle-related kinase, Cell division protein kinase 20, Cyclin-dependent protein kinase H, Cyclin-kinase-activating kinase p42, CDK20, CCRK, CDCH

应用

WB~~1:5000

产品描述

Function Required for high-level Shh responses in the developing neural tube. Together with TBC1D32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity). Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'. Cellular_Location Nucleus. Cytoplasm. Cell projection, cilium

数量

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