全部产品分类
品牌 |
Leading Biology | 货号 |
LM20096 |
产品分类 |
单克隆抗体 | 研究领域 |
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产品概述 |
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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形式 |
Voltage-dependent calcium channels control the rapid entry of Ca(2+) into a variety of cell types and are therefore involved in both electrical and cellular signaling. T-type channels, such as CACNA1I, are activated by small membrane depolarizations and can generate burst firing and pacemaker activity.
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浓度 |
CACNA1I (NP_066919, 233 a.a. ~ 331 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
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纯度 |
mouse |
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试剂准备 |
Clear, colorless solution in phosphate buffered saline, pH 7.2.
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复溶 |
Differential interactions of Na+ channel toxins with T-type Ca2+ channels. Sun H, et al. J Gen Physiol, 2008 Jul. PMID 18591418.Selective inhibition of Cav3.3 T-type calcium channels by Galphaq/11-coupled muscarinic acetylcholine receptors. Hildebrand ME, et al. J Biol Chem, 2007 Jul 20. PMID 17535809.CACNA1I is not associated with childhood absence epilepsy in the Chinese Han population. Wang J, et al. Pediatr Neurol, 2006 Sep. PMID 16939858.Association of Catsper1 or -2 with Ca(v)3.3 leads to suppression of T-type calcium channel activity. Zhang D, et al. J Biol Chem, 2006 Aug 4. PMID 16740636.International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels. Catterall WA, et al. Pharmacol Rev, 2005 Dec. PMID 16382099.
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储存条件 |
Human
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储存溶液 |
Voltage-dependent T-type calcium channel subunit alpha-1I, Voltage-gated calcium channel subunit alpha Cav33, Ca(v)33, CACNA1I, KIAA1120
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应用 |
WB~~1:500~1000
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数量 |
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