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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > BPTF Antibody

BPTF Antibody

LM20079
货号 货期 规格 / 价格 询价

BPTF Antibody

品牌

Leading Biology

货号

LM20079

产品分类

单克隆抗体

研究领域

产品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

纯度

Mouse

复溶

1. PLoS Genet. 2008 Oct;4(10):e1000241. 2. Mol Cell Proteomics. 2008 Mar;7(3):499-508.

储存条件

Human

储存溶液

Nucleosome-remodeling factor subunit BPTF, Bromodomain and PHD finger-containing transcription factor, Fetal Alz-50 clone 1 protein, Fetal Alzheimer antigen, BPTF, FAC1, FALZ

应用

E~~1/10000 WB~~1/500 - 1/2000

产品描述

Function Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors. Cellular_Location Cytoplasm. Nucleus. Note=In brains of Alzheimer disease patients, present in a subset of amyloid- containing plaques Tissue_Location Ubiquitously expressed, with highest levels in testis. Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex (at protein level)

数量

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