全部产品分类
品牌 |
Leading Biology | 货号 |
LM20064 |
产品分类 |
单克隆抗体 | 研究领域 |
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产品概述 |
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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形式 |
BCL9 is associated with B-cell acute lymphoblastic leukemia. It may be a target of translocation in B-cell malignancies with abnormalities of 1q21. Its function is unknown. The overexpression of BCL9 may be of pathogenic significance in B-cell malignancies.
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浓度 |
BCL9 (NP_004317, 1036 a.a. ~ 1135 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
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纯度 |
mouse |
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试剂准备 |
Clear, colorless solution in phosphate buffered saline, pH 7.2.
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复溶 |
Allosteric remodelling of the histone H3 binding pocket in the Pygo2 PHD finger triggered by its binding to the B9L/BCL9 co-factor. Miller TC, et al. J Mol Biol, 2010 Sep 3. PMID 20637214.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.BCL9 promotes tumor progression by conferring enhanced proliferative, metastatic, and angiogenic properties to cancer cells. Mani M, et al. Cancer Res, 2009 Oct 1. PMID 19738061.
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储存条件 |
Human
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储存溶液 |
B-cell CLL/lymphoma 9 protein, B-cell lymphoma 9 protein, Bcl-9, Protein legless homolog, BCL9
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应用 |
WB~~1:500~1000
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数量 |
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