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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > B2M Antibody

B2M Antibody

LM20059
货号 货期 规格 / 价格 询价

B2M Antibody

品牌

Leading Biology

货号

LM20059

产品分类

单克隆抗体

研究领域

产品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

形式

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. ;

纯度

Mouse

复溶

1. Cancer Immunol Immunother. 2012 Sep;61(9):1359-71. 2. Lupus. 2012 Sep;21(10):1098-104.

储存条件

Human

储存溶液

Beta-2-microglobulin, Beta-2-microglobulin form pI 5.3, B2M

应用

E~~1/10000 WB~~1/500 - 1/2000 FC~~1/200 - 1/400 IHC~~1/200 - 1/1000

产品描述

Function Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Cellular_Location Secreted. Note=Detected in serum and urine

数量

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