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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > ARHGEF11 Antibody (monoclonal) (M02)

ARHGEF11 Antibody (monoclonal) (M02)

LM20048
货号 货期 规格 / 价格 询价

ARHGEF11 Antibody (monoclonal) (M02)

品牌

Leading Biology

货号

LM20048

产品分类

单克隆抗体

研究领域

产品概述

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

形式

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.

浓度

ARHGEF11 (AAH57394, 651 a.a. ~ 750 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

纯度

mouse

试剂准备

Clear, colorless solution in phosphate buffered saline, pH 7.2.

复溶

Genome-wide association study to identify genetic variants present in Japanese patients harboring intracranial aneurysms. Akiyama K, et al. J Hum Genet, 2010 Jul 8. PMID 20613766.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.PYK2/PDZ-RhoGEF links Ca2+ signaling to RhoA. Ying Z, et al. Arterioscler Thromb Vasc Biol, 2009 Oct. PMID 19759375.The amino acid motif L/IIxxFE defines a novel actin-binding sequence in PDZ-RhoGEF. Banerjee J, et al. Biochemistry, 2009 Aug 25. PMID 19618964.On the mechanism of autoinhibition of the RhoA-specific nucleotide exchange factor PDZRhoGEF. Zheng M, et al. BMC Struct Biol, 2009 May 21. PMID 19460155.

储存条件

Human

储存溶液

Rho guanine nucleotide exchange factor 11, PDZ-RhoGEF, ARHGEF11, KIAA0380

应用

WB~~1:500~1000

数量

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