全部产品分类
品牌 |
Leading Biology | 货号 |
LM20015 |
产品分类 |
单克隆抗体 | 研究领域 |
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产品概述 |
Store at +4°C or at -20°C.
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浓度 |
Rat anti-Mouse CD123 antibody, clone 5B11 recognizes murine Interleukin-3 receptor subunit alpha, also known as CD123. CD123 is a 396 amino acid ~ 70 kDa single pass, type 1 transmembrane glycoprotein expressed on haematopoietic progenitors and most myeloid cells including basophils and mast cells. Certain mouse strains including A/J, AKR/J and NZB/B1NJ are reported to have low levels of CD123 expression due to aberrant splicing of the IL-3R alpha subunit gene.In mouse, CD123 can associate with either the common beta subunit CDw131 or with the murine IL-3 beta subunit to form a high affinity receptor for IL-3. IL-3 can bind to CD123 itself but with low affinity. Binding of IL-3 to the IL-3 receptor complex induces the proliferation and differentiation of haematopoietic cells.Rat anti-Mouse CD123 antibody, clone 5B11 does not block the binding of IL-3 to the high affinity IL-3 receptor. |
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纯度 |
Rat |
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复溶 |
1. Ichihara, M. <i>et al.</i> (1995) Impaired interleukin-3 (IL-3) response of the A/J mouse is caused by a branch point deletion in the IL-3 receptor alpha subunit gene.</br>EMBO J. 14 (5): 939-50. 2. Xu, W. <i>et al.</i> (2008) Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF. </br>J Immunol. 181:276-87. 3. O'Farrell, AM. <i>et al</i>. (1998) Signaling pathways activated in a unique mast cell line where interleukin-3 supports survival and stem cell factor is required for a proliferative response.</br>Blood. 87:3655-68.
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储存条件 |
Mouse
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储存溶液 |
Interleukin-3 receptor subunit alpha, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA, Interleukin-3 receptor class II alpha chain, CD123, Il3ra, Sut-1
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数量 |
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| 选择 | 品牌 | 货号 | 产品名称 | 规格 | 分类 | 研究领域 | 说明书 | 数量 | 目录价 | |
| 1 | Swant | 2D7 | monoclonal anti-Glutamate antibody | 200 µl | 单克隆抗体 | Antibodies against neurotransmitters |
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￥5096.00 | 订购 询价 | |
| 2 | Leading Biology | LM21248 | Anti-CD36 Antibody (Rabbit Monoclonal antibody) | 100 ul | 单克隆抗体 | Chondrogenesis Markers |
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￥4950.00 | 订购 询价 | |
| 3 | Swant | 288 | Monoclonal antibody to endothelial cells. | 单克隆抗体 |
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￥3243.00 | 订购 询价 | |||
| 4 | Swant | 345 | Monoclonal antibody to rat pyramidal cells. | 200 µl | 单克隆抗体 | Miscellaneous antibodies |
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￥3243.00 | 订购 询价 | |
| 5 | Swant | 3A12 | monoclonal anti-GABA antibody | 200 µl | 单克隆抗体 | Antibodies against neurotransmitters |
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￥5096.00 | 订购 询价 | |
| 6 | Swant | 77 | mouse monoclonal antibody against rat angiotensinogen | 200 µl | 单克隆抗体 | Antibodies against components of the renin-angiotensin system |
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￥4015.00 | 订购 询价 |
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