品牌 |
Leading Biology | 货号 |
LM20010 |
产品分类 |
单克隆抗体 | 研究领域 |
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产品概述 |
Store at +4°C or at -20°C.
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浓度 |
Rat anti-Mouse CD88 antibody, clone 10/92 recognizes murine CD88, a 45 kDa G-protein coupled cell surface receptor, otherwise known as C5aR. The CD88 molecule functions as a receptor for the complement component C5a, a potent proinflammatory molecule and chemoattractant for neutrophils to sites of infection. In mouse, CD88 is expressed on granulocytes, monocytes and macrophages but not on resting or stimulated lymphocytes.Rat anti-Mouse CD88 antibody, clone 10/92 does not block the binding of the C5a to murine CD88 (Souriet al.2003). |
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纯度 |
Rat |
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复溶 |
1. Soruri, A. <I>et al</I>. (2003) Characterization of C5aR expression on murine myeloid and lymphoid cells by the use of a novel monoclonal antibody.</br>Immunol Lett. 88:47-52. 2. Shagdarsuren, E. <i>et al.</i> (2010) C5a Receptor Targeting in Neointima Formation After Arterial Injury in Atherosclerosis-Prone Mice.</br>Circulation. 122: 1026-36. 3. Manthey, H.D. <i>et al.</i> (2011) Complement C5a inhibition reduces atherosclerosis in ApoE-/- mice.</br>FASEB J. 25: 2447-55. 4. Cudaback, E. <i>et al.</i> (2011) Apolipoprotein E isoform-dependent microglia migration.</br>FASEB J. 25: 2082-91. 5. Ager, R.R. <i>et al. </i> (2010) Microglial C5aR (CD88) expression correlates with amyloid-beta deposition in murine models of Alzheimer's disease.</br>J. Neurochem. 113: 389-401 6. Brennan, F.H. <i>et al.</i> (2015) The Complement Receptor C5aR Controls Acute Inflammation and Astrogliosis following Spinal Cord Injury.</br>J Neurosci. 35 (16): 6517-31. 7. Li, R. <i>et al.</i> (2013) C5L2: a controversial receptor of complement anaphylatoxin, C5a.</br>FASEB J. 27 (3): 855-64.
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储存条件 |
Mouse
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储存溶液 |
C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR, CD88, C5ar1, C5ar, C5r1
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数量 |
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