全部产品分类
品牌 |
Leading Biology | 货号 |
APR11959G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GABA Transporter 3 (GAT-3) antibody.
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分子量 |
69947 Da
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宿主 |
Rabbit
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种属反应性 |
Mouse, Rat
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靶点 |
Peptide (C)REARDKAVHERGH, corresponding to amino acid residues 35- 47 of rat GABA Transporter 3 (Accession P31647). Intracellular, N-terminus.Not recommended for use with human samples.
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基因ID |
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UniProt ID |
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总结 |
γ-aminobutiric acid (GABA) is the major inhibitory neurotransmitter in the mammalian central nervous system. Transmission via GABA can be halted by its reuptake through GABA transporters (GATs). These membrane proteins belong to the super family of slc6 genes which encode transporters responsible for the uptake of dopamine, serotonin, norepinephrine, glycine and GABA in a Na+-dependent manner1,2.To date, four GATs have been identified: GAT-1, GAT-2, GAT-3 and BGT-1. Like all members of the slc6 family, they have twelve transmembrane domains and short intracellular N- and C-termini1. GATs couple the transport of one GABA molecule to two Na+ ions and one Cl- ion3.GAT-3 is highly expressed in the brain and is linked to epilepsy4.Abgent is pleased to offer a highly specific antibody directed against an epitope of rat GABA Transporter 3. Anti-GABA Transporter 3 (GAT-3) antibody (#AG1232) can be used in western blot analysis, and has been designed to recognize GAT-3 from rat and mouse samples.
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形式 |
Affinity purified antibody, Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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稀释方法 |
WB~~1:200-1:2000
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别名 |
Sodium- and chloride-dependent GABA transporter 3, GAT-3, Solute carrier family 6 member 11, Slc6a11, Gabt3, Gat-3, Gat-b
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图像 |
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说明书 |
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数量 |
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