品牌 |
Leading Biology | 货号 |
APR16788G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Human Orai1 (extracellular) antibody.
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分子量 |
32668 Da
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宿主 |
Mouse
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种属反应性 |
Human
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基因ID |
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UniProt ID |
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总结 |
Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1. CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT.
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形式 |
Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, FC, ICC
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别名 |
Calcium release-activated calcium channel protein 1, Protein orai-1, Transmembrane protein 142A, ORAI1, CRACM1, TMEM142A
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图像 |
Western blot analysis using Anti-Human Orai1 (extracellular) mouse monoclonal antibody ( APR16788G), (1:200):1. HEK-293 cells transfected with human Orai1.2. HEK-293 cells transfected with control vector. Expression of Orai1 in HEK-293 transfected cells Immunocytochemical staining of intact living HEK-293 cells expressing Orai1. A. Extracellular staining of HEK-293 cells transfected with Orai1 using Anti-Human Orai1 (extracellular) mouse monoclonal antibody ( APR16788G), (red). B. Cells transfected with the empty vector show no Orai1 staining. Indirect flow cytometry analysis of intact living Jurkat cells. ——Unstained cells. ——Cells + Anti-Human Orai1 (extracellular) mouse monoclonal antibody ( APR16788G), (5-10 g antibody/0.5-1 x 106 cells). |
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说明书 |
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数量 |
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