品牌 |
Leading Biology | 货号 |
APR12763G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PCDHA6 antibody (monoclonal) (M05).
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分子量 |
102716 Da
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宿主 |
mouse
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种属反应性 |
Human
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靶点 |
PCDHA6 (NP_061732, 295 a.a. ~ 370 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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克隆号 |
1A3
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亚型 |
IgG2a Kappa
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基因ID |
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UniProt ID |
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总结 |
This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
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形式 |
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:500~1000
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别名 |
Protocadherin alpha-6, PCDH-alpha-6, PCDHA6, CNRS2
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图像 |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (34.1 KDa) . PCDHA6 monoclonal antibody (M05), clone 1A3 Western Blot analysis of PCDHA6 expression in K-562 ( (Cat APR12763G ) Detection limit for recombinant GST tagged PCDHA6 is approximately 0.3ng/ml as a capture antibody. |
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说明书 |
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数量 |
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