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> 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > TGF-alpha (Transforming Growth Factor alpha) Antibody - Without BSA and Azide品牌 |
Leading Biology | 货号 |
AMM00413G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TGF-alpha (Transforming Growth Factor alpha) Antibody - Without BSA and Azide.
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分子量 |
~6kDa
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细胞定位 |
Antigen Cellular Localization:
Transforming growth factor alpha: Secreted, extracellular space
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宿主 |
Mouse
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种属反应性 |
Human, Rabbit, Zebrafish
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克隆号 |
SPM542
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亚型 |
Mouse / IgM, kappa
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基因ID |
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UniProt ID |
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功能 |
TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.
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总结 |
This antibody reacts with the TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with this MAb is completely blocked by the peptide used for raising this antibody. TGF? ? (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
IHC-P, IF, FC
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图像 |
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说明书 |
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数量 |
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