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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > INHA Antibody

INHA Antibody

LM20490
货号 货期 规格 / 价格 询价

INHA Antibody

品牌

Leading Biology

货号

LM20490

产品分类

单克隆抗体

研究领域

产品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

纯度

Mouse

复溶

1. Cancer Epidemiol Biomarkers Prev. 2008 Dec;17(12):3567-72. 2. Acta Histochem. 2009;111(4):360-5. 3. Hum Reprod. 2009 Aug;24(8):2023-8.

储存条件

Human, Mouse

储存溶液

Inhibin alpha chain, INHA

应用

WB~~1/500 - 1/2000 IF~~1/200 - 1/1000

产品描述

Function Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. Cellular_Location Secreted. Tissue_Location Originally found in ovary (granulosa cells) and testis (Sertoli cells), but widely distributed in many tissues including brain and placenta. In adrenal cortex expression is limited to the zona reticularis and the innermost zona fasciculata in the normal gland, extending centripetally into the zona fasciculata in hyperplasia. Also found in adrenocortical tumors Also expressed in prostate epithelium of benign prostatic hyperplasia, in regions of basal cell hyperplasia and in nonmalignant regions of high grade prostate cancer. Only circulating inhibin B is found in male, whereas circulating inhibins A and B are found in female

数量

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