全部产品分类
品牌 |
Leading Biology | 货号 |
LM20466 |
产品分类 |
单克隆抗体 | 研究领域 |
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产品概述 |
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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形式 |
The protein encoded by this gene belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene has been identified for this gene.
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浓度 |
ID2 (AAH30639, 1 a.a. ~ 134 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
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纯度 |
mouse |
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试剂准备 |
Clear, colorless solution in phosphate buffered saline, pH 7.2.
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复溶 |
Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility hot-spot. Johnatty SE, et al. PLoS Genet, 2010 Jul 8. PMID 20628624.Polycomb repressor complex 2 regulates HOXA9 and HOXA10, activating ID2 in NK/T-cell lines. Nagel S, et al. Mol Cancer, 2010 Jun 17. PMID 20565746.Synergy between IL-15 and Id2 promotes the expansion of human NK progenitor cells, which can be counteracted by the E protein HEB required to drive T cell development. Schotte R, et al. J Immunol, 2010 Jun 15. PMID 20483740.Id2 promotes tumor cell migration and invasion through transcriptional repression of semaphorin 3F. Coma S, et al. Cancer Res, 2010 May 1. PMID 20388805.Inhibitor of DNA binding/differentiation 2 induced by hypoxia promotes synovial fibroblast-dependent osteoclastogenesis. Kurowska-Stolarska M, et al. Arthritis Rheum, 2009 Dec. PMID 19950294.
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储存条件 |
Human
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储存溶液 |
DNA-binding protein inhibitor ID-2, Class B basic helix-loop-helix protein 26, bHLHb26, Inhibitor of DNA binding 2, Inhibitor of differentiation 2, ID2, BHLHB26
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应用 |
WB~~1:500~1000
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数量 |
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| 6 | Swant | 3D5 | monoclonal anti-GABA antibody | 200 µl | 单克隆抗体 | Antibodies against neurotransmitters |
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