全部产品分类
品牌 |
Leading Biology | 货号 |
LM20335 |
产品分类 |
单克隆抗体 | 研究领域 |
|
产品概述 |
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
|
||
形式 |
This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.
|
||
浓度 |
FBLIM1 (NP_060026, 270 a.a. ~ 373 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
||
纯度 |
mouse |
||
试剂准备 |
Clear, colorless solution in phosphate buffered saline, pH 7.2.
|
||
复溶 |
Migfilin interacts with Src and contributes to cell-matrix adhesion-mediated survival signaling. Zhao J, et al. J Biol Chem, 2009 Dec 4. PMID 19833732.Migfilin, a molecular switch in regulation of integrin activation. Ithychanda SS, et al. J Biol Chem, 2009 Feb 13. PMID 19074766.Structural basis of the migfilin-filamin interaction and competition with integrin beta tails. Lad Y, et al. J Biol Chem, 2008 Dec 12. PMID 18829455.Colocalization of kindlin-1, kindlin-2, and migfilin at keratinocyte focal adhesion and relevance to the pathophysiology of Kindler syndrome. Lai-Cheong JE, et al. J Invest Dermatol, 2008 Sep. PMID 18528435.Increased cytoplasmic level of migfilin is associated with higher grades of human leiomyosarcoma. Papachristou DJ, et al. Histopathology, 2007 Oct. PMID 17711449.
|
||
储存条件 |
Human
|
||
储存溶液 |
Filamin-binding LIM protein 1, FBLP-1, Migfilin, Mitogen-inducible 2-interacting protein, MIG2-interacting protein, FBLIM1, FBLP1
|
||
应用 |
WB~~1:500~1000
|
||
数量 |
|
||
| 选择 | 品牌 | 货号 | 产品名称 | 规格 | 分类 | 研究领域 | 说明书 | 数量 | 目录价 | |
| 1 | Swant | 2D7 | monoclonal anti-Glutamate antibody | 200 µl | 单克隆抗体 | Antibodies against neurotransmitters |
|
￥5096.00 | 订购 询价 | |
| 2 | Leading Biology | LM21248 | Anti-CD36 Antibody (Rabbit Monoclonal antibody) | 100 ul | 单克隆抗体 | Chondrogenesis Markers |
|
￥4950.00 | 订购 询价 | |
| 3 | Swant | 288 | Monoclonal antibody to endothelial cells. | 单克隆抗体 |
|
￥3243.00 | 订购 询价 | |||
| 4 | Swant | 3A12 | monoclonal anti-GABA antibody | 200 µl | 单克隆抗体 | Antibodies against neurotransmitters |
|
￥5096.00 | 订购 询价 | |
| 5 | Swant | 345 | Monoclonal antibody to rat pyramidal cells. | 200 µl | 单克隆抗体 | Miscellaneous antibodies |
|
￥3243.00 | 订购 询价 | |
| 6 | Swant | 3D5 | monoclonal anti-GABA antibody | 200 µl | 单克隆抗体 | Antibodies against neurotransmitters |
|
￥5096.00 | 订购 询价 |
微信扫描二维码，随时随地与小诺亲密接触，精彩活动，劲爆优惠，触手可得！
销售-华东区